Image-Guided Tumorboost of Bladder Cancer
Phase 1
Completed
- Conditions
- Bladder Neoplasms
- Interventions
- Radiation: Radiation boost
- Registration Number
- NCT00963404
- Lead Sponsor
- University of Aarhus
- Brief Summary
The purpose of the study is to increase the radiation dose (Boost) to the bladder tumor. The bladder cancer patients included in the study will undergo tumor demarcation. The bladder demarcations will then be the target for an image-guided boost delivered precisely to the expected tumor site.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 19
Inclusion Criteria
- Muscle invasive bladder cancer (transitional carcinoma)
- Unifocal
- TNM stage T2a-4a, N0-1, M0
- unfit for radical cystectomy
Exclusion Criteria
- Hyperthyroidism
- Multinodular goiter
- Pregnancy
- Breast feeding
- WHO preformance status more than 2
- Iodine allergy
- MRI or CT contrast media allergy
- Bi-lateral hip-prosthesis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Tumor-boost Radiation boost Image-guided tumorboost of the bladder cancer.
- Primary Outcome Measures
Name Time Method Local tumor control One year
- Secondary Outcome Measures
Name Time Method Acute and late adverse effects of the radiotherapy treatment 3 years
Trial Locations
- Locations (4)
The department of Oncology, Aarhus University Hospital
🇩🇰Aarhus, Denmark
The department of Oncology, Rigshospitalet
🇩🇰Copenhagen, Denmark
The department of Oncology, Herlev University Hospital
🇩🇰Herlev, Denmark
The department of Oncology, Odense University Hospital
🇩🇰Odense, Denmark