NCT02697695已完成不适用
Impact of Obesity and Metabolic Surgery on Chronic Inflammation
Sana Klinikum Offenbach0 个研究点目标入组 500 人开始时间: 2014年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 500
- 主要终点
- Chronic inflammation
研究概览
简要总结
To evaluate the impact of obesity surgery on chronic inflammation.
详细描述
A retrospective study to compare the impact of laparoscopic sleeve gastrectomy (LSG), laparoscopic Roux-en Y- gastric bypass (LRYGB) and laparoscopic omega-loop gastric bypass (LOLGB) on chronic inflammation and metabolic syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI > 35kg/m² and obesity-related disease or BMI > 40kg/m²
排除标准
- •acute inflammation during laboratory examination
结局指标
主要结局
Chronic inflammation
时间窗: one day preoperatively, and 1 month, 3 month, 6 month and up to 12 month postoperatively
the changing of leucocytes in /nl after obesity surgery
次要结局
- Body Mass Index (BMI) in kg/m²(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- HbA1c(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- Fatty liver index(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- Liver enzymes(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- waist circumference(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- weight in kg(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
- Acute inflammation(one day preoperatively and one and four days postoperatively)
- Acute inflammation II(one day preoperatively and one and four days postoperatively)
- Chronic inflammation II(one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively)
研究者
Sonja Chiappetta, MD
Dr. Sonja Chiappetta
Sana Klinikum Offenbach
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