Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants

Phase 3

Completed

• Conditions: ow systemic blood flow in preterm infants; Low systemic blood flow in preterm infants; Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12607000152426
• Lead Sponsor: A/Prof Nick Evans

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-03-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Born before 30 weeks and low systemic blood flow.

Exclusion Criteria

Major intraventricular haemorrhage before intervention commences, not expected to survive.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in systemic blood flow[Measured 30 minutes after commencement of the intervention or dose change and maintained for first 24 hours after birth with repeat measures at 12 and 24 hours of age.]

Secondary Outcome Measures

Name	Time	Method
Mortality[Assessed at hospital discharge and at 1 year of ages];Intraventricular haemorrhage on serial (5,12,24 and 48 hours of age then day 7) ultrasound through the first week.[];Neurodevelopmental outcome[At 3 years of age.]