Use of Homeopathy in Patients Suffering From Long COVID-19

Completed

• Conditions: Adjustment Reaction With Physical Symptoms
• Interventions: Drug: Homeopathic medicines

• Registration Number: NCT06002230
• Lead Sponsor: Michael Frass

Brief Summary

In some patients, coronavirus (COVID-19) can cause symptoms that last weeks or even months after the infection has gone. The aim of this study was to describe the effect of adjunctive individualized homeopathic treatment delivered to Long-COVID-19 patients with previously confirmed symptomatic SARS-CoV-2 infection.

Detailed Description

All patients had been tested positive for SARS-CoV-2 before having developed Long-COVID-19 symptoms. Several testing methods were carried out in each patient to analyze a SARS-CoV-2 infection. For a confirmed infection, at least 3 out of these 5 tests had to be positive. Tests for the orthomyxoviruses influenza A and B, human metapneumovirus (hMPV) and paramyxoviruses were negative unless stated otherwise.

The homeopathic physician treated all Long-COVID-19 patients by individualized homeopathy. Repertorization of the symptoms of the current pandemic and a search in the current homeopathic literature on COVID-19 was performed using computer program. All available homeopathic medicinal products (HMPs) could be chosen by the treating physician.

Modified MONARCH criteria were assessed post hoc by all authors. Deviations were solved by discussion in person. Clinical outcome of case reports was evaluated using the "Modified Naranjo Criteria for Homeopathy-Causal Attribution Inventory". Eight points is assumed as the limit for potential correlation between homeopathic therapy and amelioration of the symptoms or healing in chronic cases.

Study Timeline

• Study Start: 2021-01-05
• Primary Completion: 2021-10-19
• Status Verified: 2023-08
• Study Completion: 2023-08-10
• Study First Submitted: 2023-08-18
• Study First Submitted QC: 2023-08-18
• Last Update Submitted: 2023-08-19
• Study First Posted: 2023-08-21
• Last Update Posted: 2023-08-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 15

Inclusion Criteria

Long COVID-19 symptoms following recovery from SARS-CoV-2 infection

Exclusion Criteria

Patients not signing informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients treated with individualized homeopathy	Homeopathic medicines	Patients suffering from symptoms of Long COVID-19 were treated with individualized homeopathy.

Primary Outcome Measures

Name	Time	Method
Modified Naranjo criteria	3 days	10 Naranjo criteria are evaluated, eight points is assumed as the limit for potential correlation between homeopathic therapy and amelioration of the symptoms or healing in chronic cases.

Trial Locations

Locations (1)

Sigmund Freud Private University; 🇦🇹 Vienna, Austria