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Clinical Trials/NCT03128307
NCT03128307
Completed
Phase 3

In-Home Study of Intraoral Device for Reducing Snoring Among Habitual Snorers

Zyppah, Inc.1 site in 1 country604 target enrollmentApril 7, 2017
ConditionsSnoring

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Snoring
Sponsor
Zyppah, Inc.
Enrollment
604
Locations
1
Primary Endpoint
Snoring Severity Scale
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Online patient registration to participate in clinical trial to test OTC mouthpiece that controls position of the tongue to reduce snoring.

Detailed Description

Patient will complete informed consent, inclusion/exclusion criteria, sleep apnea and snoring surveys online. If patient meets all criteria for the study, patient will be provided with a treatment device for use for a 10 day treatment period. Patient will complete the trial upon providing final online surveys.

Registry
clinicaltrials.gov
Start Date
April 7, 2017
End Date
August 10, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Over 18 years of age
  • Living in the United States
  • Signing the Informed Consent Form

Exclusion Criteria

  • Missing teeth (as the device won't be properly fitted)
  • Any severe breathing or respiratory disorder, such as chronic asthma, emphysema, COPD, or a similar condition
  • Poor dental health, such as severe gum disease, loose teeth, an abscess, mouth sores, or bleeding gums
  • A dental implant placed within the last three months
  • Diagnosed with a Temporomandibular joint condition (TMJ)
  • Actively experiencing any mouth or jaw pain, including clenching of the teeth, grinding, or any other physical injury to the jaw or teeth
  • Full dentures
  • Diagnosis of sleep apnea
  • Less than 18 years of age

Outcomes

Primary Outcomes

Snoring Severity Scale

Time Frame: Baseline and 10 Days

The Snoring Severity Scale (SSS) is a 9-point, validated scale to measure the severity of snoring. A total of three questions are asked: 1) "How often do you snore, 2) "How long do you snore", and 3) How audible is your snoring. Answers for each of these questions are summed for a total SSS score. A score of '0' would indicate no snoring at all, while a score of '9' would indicate the most severe snoring as measured by the SSS. Outcome measure reported as change with use of the device over pre-trial. In this case, a negative ('-') would represent improvement in snoring symptoms, while a positive ('+') number would indicate an increase in snoring severity.

Visual-Analogue Scale, Self-Reported Snoring Habits

Time Frame: Baseline and 10 Days

Quantitative assessment on 1-10 scale. Outcome measurement reported as a percentage change from pre-trial with use of the device. A negative ('-') percentage would indicate a reduction in snoring symptoms as measured by the VAS, while a positive percentage ('+') result would indicate an increase in the measured symptom.

Study Sites (1)

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