Arthroscopic Rotator Cuff Repair With Platelet-Rich Plasma(PRP) in Large to Massive Tears : A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Rotator Cuff Tear
- Sponsor
- Seoul National University Hospital
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- structural integrity of repaired rotator cuff tendon
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
- The purpose of this study is to compare the clinical and anatomical outcomes of rotator cuff repair with Platelet-Rich Plasma(PRP) and conventional rotator cuff repair in treatment of large to massive rotator cuff tears.
- PRP application to arthroscopic rotator cuff repair would accelerate recovery after arthroscopic rotator cuff repair in terms of pain relief, functional outcomes, overall satisfaction, and enhance structural integrity of repaired tendon.
Investigators
Hyunchul Jo
Assistant Professor, SMG-SNU Boramae Medical Center.
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •large to massive rotator cuff tear as a determined by clinical examination and MR prior to surgery.
Exclusion Criteria
- •previous history of shoulder surgery
- •acute trauma
- •chronic dislocation
- •pyogenic infection
- •rotator cuff arthropathy with glenohumeral osteoarthritis and superior migration of the humeral head
- •showed abnormal serological test results
- •thrombocytopenia (platelets less than 15000 per microliter)
- •had been received anti-platelet medication
- •psychiatric problems that precludes informed consent or inability to read or write
- •other serious problems that preclude participation of the study
Outcomes
Primary Outcomes
structural integrity of repaired rotator cuff tendon
Time Frame: postoperative 9months
To evaluate structural outcomes, magnetic resonance(MR)imaging or computed tomography arthrography were used at minimum postoperative 9months. The structural integrity was evaluated using Sugaya's method; * type I, sufficient thickness with homogenously low intensity * type II, insufficient thickness partial high intensity * type III, insufficient thickness without discontinuity (thinned cuff) * type IV, presence of minor discontinuity * type V, presence of a major discontinuity Type I, II, and III were considered as healed, while type IV, and V were considered as retear.