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The association between atrophic gastritis and Helicobacter pylori eradicatio

Not Applicable
Conditions
Diseases of the digestive system
Registration Number
KCT0003851
Lead Sponsor
Yonsei University, Wonju Severance Christian Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
220
Inclusion Criteria

(1) Men or women aged 19 to over 80
(2) Atrophic gastritis is seen (a significant range of mucosal pale and sparkling submucosal blood vessels are markedly observed, Kimura classification can be applied), and H. pylori test (CLO) positive
(3) Patients who agreed to the study
(4) Patients who desire H. pylori eradication

Exclusion Criteria

(1) H. pylori test (CLO) negative
(2) Severe systemic or coagulopathic disorders
(3) previously treated for H. pylori eradication
(4) If there is a previous history of antibiotic treatment before 4 weeks of the start of study
(5) Patients with a history of gastrectomy
(6) Patients have allergies to antibiotics
(7) Pregnant or lactating women

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identification of risk factors associated with eradication of H. pylori in patients with atrophic gastritis
Secondary Outcome Measures
NameTimeMethod
Success rate of H. pylori eradication in atrophic gastritis;Level measurement of Pepsinogen I and II;clarithromycin resistance;Compliance of antibiotics
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