Determinants of successful discontinuation of antipsychotics used for behavioural symptoms in people with intellectual disability
Completed
- Conditions
- challenging behaviour1005716710037173
- Registration Number
- NL-OMON40740
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Any sex or ethnicity
Age >= 6 years
Functioning below an IQ level of 70 as assessed by an authorized behavioral scientist
Subjects have used one or more antipsychotics for more than one year for challenging behavior
Subjects have been presented a treatment proposal of an attempt to discontinue antipsychotics by their physician.
Exclusion Criteria
A history of schizophrenia, a bipolar disorder, or affective psychosis according to DSM IV or ICD-10 criteria
A history of unsuccessful withdrawal of antipsychotics in the past 6 months
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Behavioral parameters are scores of the five subscales of the Aberrant Behavior<br /><br>Checklist (ABC) i.e., irritability, hyperactivity, lethargy, stereotypic<br /><br>behavior and inappropriate speech, and of the Clinical Global Impression scale<br /><br>Improvement (CGI-I). </p><br>
- Secondary Outcome Measures
Name Time Method