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Short TEG: cessation of clopidogrel following insertion of drug-eluting coronary stents

Completed
Conditions
Topic: Cardiovascular
Percutaneous coronary intervention
Subtopic: Cardiovascular (all Subtopics)
Circulatory System
Disease: Cardiovascular
Registration Number
ISRCTN51917813
Lead Sponsor
Southampton University Hospitals NHS Trust (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

1. Aged greater than 18 years, either sex
2. Signed written informed consent
3. Prior percutaneous coronary intervention (PCI) with drugeluting stent implantation and due to stop clopidogrel 12 months after PCI
4. On maintenance dose aspirin 75 mg and clopidogrel 75 mg daily
5. 30 diabetics and 30 nondiabetics

Exclusion Criteria

1. Aged greater than 85 years
2. On regular nonsteroidal antiinflammatory medication or steroids

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clopidogrel is routinely used for 12 months after drugeluting stent implantation
Secondary Outcome Measures
NameTimeMethod
Any differences in inflammatory markers, measured at 12 months
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