Effect of Curcumin associated with LED application in the treatment of residual pockets of patients with Chronic Periodontitis and type 2 Diabetes Mellitus
- Conditions
- Chronic Periodontitis, Diabetes MellitusC07.465.714.533.324C18.452.394.750.149
- Registration Number
- RBR-4tq9yq
- Lead Sponsor
- niversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatuba
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Patients with age equal to or greater than 30 years and less or equal than 70 years (MATARAZZO et al., 2008); diagnosis of chronic periodontitis that have undergone periodontal treatment in a period of 3 to 6 months, with at least 4 sites with probing depth (PD) bigger or equal than 5 mm and loss of clinical attachment (CAL) bigger or equal than 3 mm with bleeding on probing (BOP) (APP, 2015); patients diagnosed with type 2 diabetes mellitus (HbA1c equal to or greater than 6.5%) (SACKS et al., 2011); present at least 15 teeth, excluding third molars (ASSEM, 2015); at least 1 site with PD equal to or greater than 5 mm (residual pocket with bleeding on probing) per quadrant.
Smokers or ex-smokers for more than 12 months; patients with anemia; patient with active cancer and history of chemotherapy; history of antibiotic therapy in the previous 6 months; history of anti-inflammatory therapy in the last 6 months; patient with blood disorders; pregnancy; patient in orthodontic treatment.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of the study will be the mean of changes in the level of clinical attachment in moderate and deep pockets.<br><br>
- Secondary Outcome Measures
Name Time Method Clinical evaluation of visible plaque index, bleeding on probing, gingival recession and probing depth after 90 and 180 days of periodontal treatment.