MedPath

Cardiological Drug Classes And Falls in Older Adults

Completed
Conditions
Heart Failure
Fall
Registration Number
NCT07150754
Lead Sponsor
University Hospital, Caen
Brief Summary

Heat failure is a fast gowing health issue with a rising incidence in older adults. Recommendations have recently been published to treat heart failure, but most clinical trials leading to these recommendations tended to exclude older adults.

Older adults are at higher risk of falls and severe consequences of falls. All heart failure treatments are at risk of causing a fall through different mechanisms.

Based on the World Health Organization global database, the main objective of this study is to investigate the association between heart failure pharmacological treatments and the report of a fall in the database.

A disproportionality analysis will be performed. It will aim to assess whether some classes of heart failure drugs, and within these classes some individual drugs, are associated with a report of a fall.

A sensibilty analysis will also be performed. It will aim to examine the association between takien a heart failure pharmacological treatment, with a heat failure indication and/or a loop diuretic, and the report of a fall.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100000
Inclusion Criteria
  • Age 65 years of older
Exclusion Criteria

-

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Report of a fall with a recommended pharmacological treatment for heart failure02/11/2024
Secondary Outcome Measures
NameTimeMethod
Sensibility analysis02/11/2024

Reports of falls with one or more of the respective drug classes that also had either "furosemide" prescription and/or "heart failure" as indication

Trial Locations

Locations (1)

Caen University Hospital, Department of Pharmacology

🇫🇷

Caen, Normandy, France

Caen University Hospital, Department of Pharmacology
🇫🇷Caen, Normandy, France

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