The Optimization of Medications in Chronic Heart Failure Using a Website

Not Applicable

Terminated

• Conditions: Heart Failure
• Interventions: Other: Med Optimization Arm

• Registration Number: NCT04580004
• Lead Sponsor: University of Michigan

Brief Summary

Heart failure (HF) is the most common hospital discharge diagnosis among older adults in the United States. Strikingly, 2 in 5 patients are readmitted within 1-year following their first HF admission. This results in significant potentially avoidable costs to our already strained healthcare system since hospitalizations result in 70% of yearly HF management costs. One of the most common causes of readmission is lack of medication optimization. This study will determine the effectiveness of a medication optimization website.

Detailed Description

In a prospective design, 100 patients will be randomized to the intervention or usual care in a 1:1 fashion. Patients randomized to the intervention will receive an evidence-based medication recommendation intervention. Outcome measures will be collected at baseline and at 2 weeks post-intervention.

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study Start: 2020-09-24
• Study First Submitted: 2020-10-01
• Study First Submitted QC: 2020-10-01
• Study First Posted: 2020-10-08
• Primary Completion: 2021-02-08
• Study Completion: 2021-02-08
• Status Verified: 2022-01
• Last Update Submitted: 2022-01-24
• Last Update Posted: 2022-02-08

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• left ventricular ejection fraction (LVEF) </= 40%

Read More

Exclusion Criteria

• pregnancy
• active cancer with a life expectancy less than 12 months
• hospice
• chronic inotropic therapy

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Medication Optimization Group	Med Optimization Arm	Patients randomized to the medication optimization group will receive an evidence-based medication recommendation intervention.

Primary Outcome Measures

Name	Time	Method
The change in medications will be measured by the Evidence Based Medicine Percent Score (EBMPS).	Change over 2 weeks	The Evidence Based Medicine Percent Score (EBMPS) is calculated by the medications and doses the patient is taking (in points) divided by the total eligible medications based on the evidence (in points).

Trial Locations

Locations (1)

University of Michigan; 🇺🇸 Ann Arbor, Michigan, United States