ACTRN12622000908730
Active, not recruiting
未知
Efficacy and neural mechanisms of computerised cognitive training in Huntington’s disease: A randomised controlled trial
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Monash University
- Enrollment
- 30
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion criteria include:
- •(a) Genetically positive for Huntington’s disease (HD)
- •(b) Premanifest disease or early\-stage manifest disease (total functional capacity \[TFC] \= 7\-13\)
- •(c) 18\+ years of age
- •(d) Access to computer with Internet connection
Exclusion Criteria
- •Exclusion criteria include:
- •(a) Absence of known genetic confirmation for HD
- •(b) Late\-stage disease (TFC \< 7\)
- •(c) Under 18 years of age
- •(d) Diagnosis of any major neurological or psychiatric condition other than HD (besides anxiety or depression), history of substance abuse or head injury
- •(e) Severe depression and anxiety symptoms (score \> 14 on either HADS subscale)
- •(f) Unstable dose of medication for depression and anxiety in the last 6 months
- •Additional exclusion criteria if undergoing MRI:
- •(a) Left\-handed
- •(b) Currently pregnant
Outcomes
Primary Outcomes
Not specified
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