Comparison of BIA with daily weight, intake-output with in sepsis and septic shock patients

Not yet recruiting

Conditions: Certain infectious and parasitic diseases, (2) ICD-10 Condition: B955||Unspecified streptococcus as the cause of diseases classified elsewhere,

Brief Summary: Fluid resuscitation is essential component of sepsis bundle, initial fluid resuscitation can increase the stroke volume and restore organ perfusion. However, excess fluid thereafter may damage vascular integrity leading to tissue demand organ dysfunction. Cumulative fluid balance (CFB) is total amount of fluid accumulates in body over a period of time. High CFB can increase time on mechanical ventilator, length of ICU stays and mortality.

There are various surrogate markers for CFB (e.g.-Daily weight, calculated fluid balance, clinical assessment of edema, skin turgor, lung edema, thirst, CVP) but its less subjective, poorly validated.

Bioimpedance analysis (BIA) along with calculated fluid balance, daily weight measurement will help in maintaining CFB. Calculated fluid balance is most easy, feasible and vastly used method. Intake -output calculation is considered as gold standard for CFB, but it doesn’t measure insensible loss. Daily weight measurement in ICU patient is tedious task, less precise. BIA measures electrical impedance by passing weak and small alternating current through body. It not only calculates total body water (TBW) but Intracellular weight (ICW) and Extracellular water (ECW) as well. Hence, the need to assess merit of BIA against the above parameters

Recruitment & Eligibility

Inclusion Criteria

Any patients with sepsis and or septic shock requiring ionotropic supports.

Exclusion Criteria

CKD patients Amputee Trauma patients Post op or surgical patients Patient with LV dysfunction.

Primary Outcome Measures

Name	Time	Method
Compare BIA with daily weight and intake output for cumulative fluid balance in sepsis and septic shock	6months

Secondary Outcome Measures

Name	Time	Method

Locations (1): SL Raheja
🇮🇳
Mumbai, MAHARASHTRA, India
SL Raheja
🇮🇳Mumbai, MAHARASHTRA, India
Dr Sanjith Saseedharan
Principal investigator
9004479549
docsanjith@rediffmail.com