NCT02806388
Recruiting
Not Applicable
Individualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project
National Cancer Centre, Singapore1 site in 1 country5,500 target enrollmentOctober 2011
ConditionsSolid Tumor
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Solid Tumor
- Sponsor
- National Cancer Centre, Singapore
- Enrollment
- 5500
- Locations
- 1
- Primary Endpoint
- The molecular and clinical epidemiology for cancer patients being considered for novel therapeutics
- Status
- Recruiting
- Last Updated
- 10 months ago
Overview
Brief Summary
This study aims to screen tumor molecular profile for better selection of anticancer treatment, in particular, allocation to clinical trials if available.
Detailed Description
Molecular profiling will be performed on archival tumor tissue or freshly collected tumor tissue from re-biopsy. Blood, pleural fluid, FNA, and/or saliva may be collected to study the genetic makeup and also to compare the tumor molecular profile. Personalized therapy will be given based on molecular profile.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Confirmed histological diagnosis of solid tumor
- •Suitable for systematic treatment and clinical trials
- •ECOG (Eastern cooperative oncology group) performance status \< 2
- •Able to provide tumor tissue for molecular profiling
- •Able to understand and sign the informed consent form
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
The molecular and clinical epidemiology for cancer patients being considered for novel therapeutics
Time Frame: 5 years
Secondary Outcomes
- The correlation of molecular profiles with clinical outcomes(5 years)
- The proportion of patients who have actionable alterations and enrol into clinical trials(5 years)
Study Sites (1)
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