Glutamine supplementation guided by plasma glutamine levels
Withdrawn
- Conditions
- voeding supplementenglutamine
- Registration Number
- NL-OMON42972
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
All patients admitted to the ICU with an expected stay of 48 hours or longer
Exclusion Criteria
age under 18 years, readmission to the ICU, contra-indication for enteral nutrition and the use of Total Parental Nutrition
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Is there a difference in length of mechanical ventilation, length of stay ICU<br /><br>or length of stay hospital between patients who received enteral glutamine or<br /><br>not?</p><br>
- Secondary Outcome Measures
Name Time Method <p>What is the amount of enteral glutamine supplementation needed to increase the<br /><br>plasma glutamine level to a level above 420 µmol/l.Is there a difference<br /><br>between hospital mortality or 6 month mortality between patients who received<br /><br>enteral glutamine or not?<br /><br>Is there a relationship between nutritional status ( measured with<br /><br>bio-impedance vector analysis) and plasma glutamine level?<br /><br>Is there a relationship between the amount of supplied nutrition and the course<br /><br>of plasma glutamine levels?<br /><br>Is there a difference between patients admitted with sepsis or trauma compared<br /><br>to other causes of admission?</p><br>