HIIT-the track: High Intensity Interval cycle-ergometer exercise Training in people with Parkinson*s Disease
- Conditions
- Parkinson's Disease10028037
- Registration Number
- NL-OMON49269
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 4
Inclusion Criteria
1) diagnosis of PD according to brain bank criteria, 2) Hoehn-Yahr stage I (n<=2
patients) and III (n<=2 patients), 3) sufficient cognition to comprehend
training instruction (Moca score >21) and 4) able to provide written informed
consent.
Exclusion Criteria
1) history of neurologic deficits other than PD, 2) severe fluctuating
responses to medication, 3) psychiatric, musculoskeletal, cardiac or metabolic
disorders prohibiting participation in intensive exercise training.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Outcome measures include disease status (UPDRS)</p><br>
- Secondary Outcome Measures
Name Time Method <p> blood biomarkers for plasticity (BDNF and Neurofilament Nfl), and measures for<br /><br>walking and balance, as well as cognition, mood and biorhythm (sleeping<br /><br>problems).</p><br>