CTRI/2026/01/101524尚未招募1 期
Comparative study of the efficacy of Lidocaine vs Magnesium sulphate nebulization on attenuation of intubation response in patients undergoing general anaesthesia
Jss Academy of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年1月27日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare the efficacy of magnesium sulfate and lidocaine on attenuation of intubation response.
研究概览
简要总结
Patients admitted to JSS hospital, undergoing elective surgery requiring general anaesthesia with endotracheal intubation, after applying inclusion and exclusion criteria, will be subjected to the study. Nebulization will be given with visira nebulizer mask, 30 minutes prior to induction and endotracheal intubation.
Study parameters to be assessed are-
-
Hemodynamic changes observed at 0, 1, 3, 5, 10 minutes from time of intubation.
-
Incidence of postoperative sore throat.
-
Sedation in postoperative period
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Age group of 18 years to 60 years
- •Patients belonging to American Society of Anesthesiologists grade 1 and 2 posted for surgery under general anaesthesia requiring endotracheal intubation.
排除标准
- •Patient refusal
- •History of allergy to the study drugs
- •Parturients.
结局指标
主要结局
To compare the efficacy of magnesium sulfate and lidocaine on attenuation of intubation response.
时间窗: 18 months
次要结局
未报告次要终点
研究者
DR. R NANDHINI
Jss Medical College and Hospital, Mysore, Karnataka
研究点 (1)
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