Multiphoton microscopy for sectioning-free H&E histology in dermatology
- Conditions
- Basal cell carcinomas and squamous cell carcinomas
- Registration Number
- DRKS00034501
- Lead Sponsor
- Klinik für Dermatologie, Allergologie und Venerologie, UKSH Campus Lübeck
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Tumour resection planned, capable of giving consent
Exclusion Criteria
none
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A 3-4 mm skin punch is extracted from tissue from surgical resectates after removal. This is handed over to the employees of Histolution GmbH. The samples are stained in the Histolution GmbH laboratory and then scanned with the MPM. The skin punches are then sent to the pathology laboratory for routine diagnostics. The scanned images are then examined by one or more pathologists and compared to the routine histological diagnosis.
- Secondary Outcome Measures
Name Time Method Staining time, type of dyes used, laser power, exposure time, amplification of the detectors, scaling of the values in the subsequent image