TIME OF ADMINISTRATION OF TRANEXAMIC ACID TO PREVENT BLEEDING IN TOTAL KNEE ARTHROPLASTY

Consorci Mar Parc de Salut de Barcelona (Parc de Salut MAR)0 个研究点开始时间: 2016年2月3日最近更新: 2016年5月2日

适应症

试验速览

暂无简介。

•-Adult patients of both genre aged between 18 and 85 years.
•- Patients scheduled for primary and unilateral total knee arthroplasty with tourniquet.
•- Patients who signed informed consent indicating that they have been informed of all pertinent aspects of the trial.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 32
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 160

•-Pregnancy or risk of pregnancy ( fertile women who do not take contraceptives) or lactating.
•- Participation in a clinical drug research before 3 months in pre-drug administration.
•- Congenital or acquired bleeding disorder including thrombophilia.
•- Absolute or relative contraindications of tranexamic acid administration :
•- venous or arterial thrombosis
•- pulmonary thromboembolism
•- paroxysmal atrial fibrillation
•- chronic kidney failure with GFR <40mm
•- epilepsy (seizures in the last year)

发起方