A randomized controlled study of Zhu's Tiaojing Recipe on blood lipid in patients with obese polycystic ovary syndrome
- Conditions
- Polycystic ovary syndrome
- Registration Number
- ITMCTR2100005338
- Lead Sponsor
- Yueyang integrated traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
1.3 Inclusion Criteria
(1) Women aged between 18 and 40;
(2) Meet the diagnostic criteria of Western medicine for polycystic ovary syndrome;
(3) BMI 25 kg/m2 or;
(4) No hormone or lipid-lowering drugs were taken within 3 months before entering the study;
(5) Patients signed informed consent and volunteered to take the test.
1.4 Exclusion Criteria
(1) persons younger than 18 or older than 40;
(2) those who had used drugs and contraceptives affecting endocrine and lipid metabolism within 3 months before the study;
(3) allergic to metformin;
(4) Gynecological examination or B ultrasound examination of organic lesions of the uterus and accessories;
(5) Diseases similar to the clinical and endocrine signs of PCOS due to other reasons, such as follicular membrane cell hyperplasia, ovarian or adrenal tumor, adrenal cortical hyperplasia, etc.;
(6) patients with serious primary diseases such as heart disease, liver disease and kidney disease or mental illness;
(7) Those who do not meet the inclusion criteria, do not use drugs as prescribed, cannot judge the efficacy or incomplete data affect the judgment of efficacy or safety.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total effective rate of clinical efficacy;
- Secondary Outcome Measures
Name Time Method Fasting plasma glucose;Follicle stimulating hormone;triglycerides;High-density lipoprotein;body mass index;TCM syndrome score;progesterone;Total cholesterol;weight;free fatty acids;testosterone;Estradiol;Prolactin;Waist hip ratio;Fasting insulin;Ovarian volume;Luteinizing hormone;Follicle diameter;Endometrial thickness;LH/FSH;Number of antral follicles;Low-density lipoprotein;