Evaluating the effects of symbiotic therapy in male infertility with idiopathic oligoastenospermia
- Conditions
- Idiopathic oligoasthenospermia.
- Registration Number
- IRCT20190810044500N6
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- 40
Age 20 to 50 years
Sperm concentration below 15 million per cc
Percentage of progressive motile spermatozoa < 32%
Total ejaculated spermatozoa<39*106
Total motility <40%
Normal serum levels of free testosterone, Prolactin, Luteinizing hormone, Follicle-stimulating hormone
Drug or alcohol abuse
Concentration of white blood cells in semen > 106 per cc
Possibility of being treated with gonadotropins, anabolic steroids, cancer chemotherapy, NSAIDs, infertility medications in the last two months
Previous history of chemotherapy or radiotherapy for cancer
Existence of palpable varicocele
X-ray history of the past eight months
Y chromosome microdeletion
Karyotype alterations
Testicular atrophy and testicular failure
Other secondary causes of infertility
A history of liver problems and a history of allergy to clomiphene
Percentage of typical forms<4%
Ejaculated volume <1.5 ml
Abnormal serum levels of free testosterone, Prolactin, Luteinizing hormone, Follicle-stimulating hormone
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sperm concentration in semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Sperm motility in semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Sperm morphology in Semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Semen fluid volume. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Semen fluid Power Hydrogen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Serum concentration of free testosterone, prolactin, luteinizing hormone, follicle-stimulating hormone. Timepoint: Before the intervention and after the intervention. Method of measurement: Blood test.
- Secondary Outcome Measures
Name Time Method Age. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire.;Height. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire.;Weight. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire.