Impact of Left Atrial Function on Postoperative Atrial Fibrillation

Completed

• Conditions: Atrial Fibrillation

• Registration Number: NCT00646997
• Lead Sponsor: Florence Nightingale Hospital, Istanbul

Brief Summary

We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

Detailed Description

Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Study Timeline

• Study Start: 2008-03
• Study First Submitted: 2008-03-26
• Study First Submitted QC: 2008-03-28
• Study First Posted: 2008-03-31
• Primary Completion: 2008-05
• Study Completion: 2008-05
• Status Verified: 2008-06
• Last Update Submitted: 2008-06-27
• Last Update Posted: 2008-06-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 1Coronary artery disease evidenced by coronary angiography
• 2Patients with a decision of undergoing elective coronary artery bypass greft operation
• 3Sinus rhythm in electrocardiography

Exclusion Criteria

• 1Rheumatic valve disease
• 2Having prosthetic valve
• 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
• 4Left ventricular l ejection fraction <40%
• 5Mild to moderate mitral stenosis or regurgitation
• 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
• 7Congenital heart disease
• 8Chronic liver disease
• 9Chronic renal disease
• 10Malignancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Velocity vector imaging derived left atrial segmenter function, Tissue doppler derved left atrial segmenter function, conventional analysis of atrial function by 2D and pulsed wave echocardiography.	April 2008

Trial Locations

Locations (1)

TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology; 🇹🇷 Istanbul, Turkey