Comparison of macular thickness and inflammatory cytokine levels after microincision versus small incision coaxial cataract surgery

Not Applicable

Completed

• Conditions: Cataract; Eye Diseases; Cataract, unspecified

• Registration Number: ISRCTN69290731
• Lead Sponsor: The National Research Foundation of Korea (NRF) (South Korea)

Brief Summary

2016 results in https://pubmed.ncbi.nlm.nih.gov/25828946/ (added 17/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2010-12-01
• Study Start: 2014-01-03
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

Eyes with nuclear density from Grade 3 to 4

Exclusion Criteria

1. Corneal pathology
2. Pseudoexfoliation
3. History of ocular trauma
4. Intraoperative complications such as posterior lens capsule rupture, lens dislocation and ocular inflammation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Intraoperative measurements included:<br> 1.1. Ultrasound time (UST)<br> 1.2. Mean cumulative dissipated ultrasound energy (CDE)<br> 1.3. Total balanced salt solution (BSS) use<br> 2. Clinical measurements included preoperative, 1-week postoperative, 1-month postoperative and 2-month postoperative:<br> 2.1. Best corrected visual acuity (BCVA)<br> 2.2. Central corneal thickness (CCT)<br> 2.3. Endothelial cell count (ECC)<br>

Secondary Outcome Measures

Name	Time	Method
Enzyme-linked immunosorbent assay (ELISA) and reverse transcription polymerase chain reaction (RT-PCR) were performed for IL-1alpha, IL-6, VEGF and PGE2 preoperatively and at 1 week postoperatively