Evaluation and comparison of the effect of Leukocyte platelet rich fibrin and advanced platelet rich fibrin in the rate of orthodontic tooth movement: A split mouth study.
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- acceleration rate of tooth movement
研究概览
简要总结
Various studies have been conducted using different pharmacological agents where the rate of tooth retraction is evaluated(El-Timamy et al., 2020; Erdur et al., 2021; Rashid et al., 2017). Studies have been conducted to evaluate the rate of orthodontic tooth movement following placement of L-PRF with conflicting results based on mode of administration (KV Balarama et al.,2023; Reyes Pacheco et al., 2020; Tehranchi et al., 2018). Studies also have been conducted to evaluated the rate of tooth movement in wilckodontics followed by bone graft mixed with A-PRF (D et al., 2020). There are no studies available in literature regarding the comparison of effect of A-PRF and L-PRF when used in plug form on rate of orthodontic tooth movement. Also, no studies have compared the rate of tooth movement when extractions were done in the beginning of treatment vs extractions done just before retraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 14.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Class I Bimaxillary cases needing all 4 extractions
- •Between age group of 14 to 30years.
排除标准
- •Patients under any other medication which affects tooth movement
- •Patients with craniofacial anomalies
- •Patients with periodontal disease
- •Patients with any kind of systemic disease that affects tooth movement
- •Patients in pregnancy or lactation
- •Patients with habits of smoking and alcoholism.
结局指标
主要结局
acceleration rate of tooth movement
时间窗: At baseline, after 1week, after 2week, after 1month, after 2months, after 3months, after 4months
次要结局
- root resorption & tooth vitality(Just before intervention & after 4 months)
研究者
Dr Deepthi D
M S Ramaiah dental college