Effect of oral and vaginal administration probiotic in treatment of women with vaginal candidiasis

Phase 2

• Conditions: Vulvovaginal Candidiasis.; Candidiasis of vulva and vagina; B37.3

• Registration Number: IRCT2016090529710N1
• Lead Sponsor: Kashan University of Medical Scinces and Health Services

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

married women aged 18-45 years old
none pregnant
absence of menstruation at the time of attendance
not using vaginal medications, antibiotics , immonosupressive drugs and exogenous hormones such as oral contraceptives since 2 weeks before starting the research; not having intercourse or using vaginal douche within the last 24hours
absence of any diagnose medical disease such as diabetis and other auto immune diseases, by asking the patient
not having intercourse or using vaginal douche within the last 24 hours
verification of vulvovaginal candidiasis resulted clinical symptoms and KOH positive smear and culture

Exclusion Criteria

allergic reactions to fluconazole, lactovag and lactofem
pregnancy during therapy
compulsion to use antibiotics or other anti fungal drugs.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vaginal candidiasis symptoms. Timepoint: 35-30 days after starting probiotic or placebo treatment. Method of measurement: questionnaire.

Secondary Outcome Measures

Name	Time	Method
Dirct smear and Culture. Timepoint: 30-30 days after starting treatment with fluconazole and probiotic or placebo. Method of measurement: culture and direct smear.