The effect of Biotin on blood glucose and plasma lipids in diabetic patients
Phase 2
- Conditions
- Diabetes.Insulin-dependent diabetes mellitus
- Registration Number
- IRCT201110027691N1
- Lead Sponsor
- Vice Chancellor for Research and Technology of Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
HbA1C more than 8% and history of diabetes type 1 for at least one year; age of 5-25 years old.
Exclusion criteria : history of renal and cardiac disease, seizure, using corticosteroids or anti-convulsive drugs, also history of hypoglycemic attacks or ketoacidosis during past 3 months, and pregnancy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hg A1C. Timepoint: at the baseline and 3 months after intervention. Method of measurement: labratory test (Nycocard kits).;Lipiod profile (cholesterol, triglycerides, low dencity lipoprotein, high dencity lipoprotein). Timepoint: before intervention and after 3 months. Method of measurement: laberatory method.
- Secondary Outcome Measures
Name Time Method Advers effects such as hypoglycemia, no tolerance to biotin. Timepoint: during the intervention. Method of measurement: self monitoring blood sugar by subjects.