IRCT20230517058211N1招募中3 期
Comparison of efficacy and safety of intravenous cyclophosphamide and steroids with oral cyclophosphamide and steroids in the treatment of idiopathic membranous nephropathy
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 58
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 80 years（—）
- 性别
- All
入选标准
- •Serum Anti-Phospho Lipase A2 Receptor positive or IgG4 positivity on Immunofluorescence.
- •Biopsy –proven Idiopathic Membranous Nephropathy, moderate risk group (Spot Urine protein/ spot urine creatinine Ratio between 4 to 8 g/g) that has failed to respond to conservative therapy for 6 months.
- •Biopsy–proven Idiopathic Membtanous Nephropathy high risk group (Spot Urine protein/ spot urine creatinine Ratio more than 8g/g).
排除标准
- •Patients with clinical, histologic, or serologic evidence of secondary Membranous Nephropathy.
- •Evidence of Hepatitis B/C and Human Immunodeficiency Virus
- •Evidence of malignancy (Prostate Specific Antigen, Mammogram, Chest x-ray.)
- •Active or ongoing infection/ Recent infection.
- •Allergy to cyclophosphamide.
- •Contraindication to steroid/ cyclophosphamide
研究者
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