Mastocytosis Registry (of Zurich)

Recruiting

• Conditions: Hypertryptasemia; Mastocytosis

• Registration Number: NCT06466889
• Lead Sponsor: University of Zurich

Brief Summary

The study aims to summarize patients with mastocytosis and hypertryptasämia (without underlying mastocytosis or no bone marrow biopsy) in relation to demographic information, clinical progress and treatment courses. Biologic samples are collected from available routine diagnostics (serum, skin tissue, gut mucosa, bone marrow, and others) for further use in experimental research.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-06
• Study Start: 2024-06-06
• Study First Submitted: 2024-06-13
• Study First Submitted QC: 2024-06-18
• Study First Posted: 2024-06-20
• Last Update Submitted: 2024-06-24
• Last Update Posted: 2024-06-26
• Primary Completion: 2025-12-31
• Study Completion: 2035-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Adult patients with mastocytsis/hypertryptasemia which are treated at the university hospital of Zurich
• available informed consent

Exclusion Criteria

• denied consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Demographics	2010-2025	In the registry we collect patient's demographic data e.g. age, gender, comorbidities, smoking, preexisting atopic disease and other to look for associations to mast cell diseases.
Disease progression	2010-2025	Patients will followed up over time to get more insight in disease progression.If there is progression detected (e.g. cutaneous mastocytosis to systemic mastocytosis or ISM to advanced forms) those cases will be carefully looked at to identify triggering factors and biomarkers.

Trial Locations

Locations (1)

University Hospital of Zurich; 🇨🇭 Zurich, Switzerland