NCT02315391已完成不适用
Efficacy of Isolated Whey and Micellar Whey Protein (+/- Citrulline) to Stimulate Protein Synthesis in 'Healthy' and 'Anabolically Resistant' Elderly Muscle
Société des Produits Nestlé (SPN)0 个研究点目标入组 30 人开始时间: 2012年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 主要终点
- Change in myofibrillar fractional synthetic rate (FSR)
研究概览
简要总结
The primary objective is to determine the effect of reduced activity on the stimulation of myofibrillar FSR with protein feeding in the elderly.
详细描述
The primary objective is to determine the effect of reduced activity on the stimulation of myofibrillar FSR with protein feeding in the elderly
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Must habitually complete a minimum of 5000 steps per day
- •Having obtained informed consent
- •Non-obese
- •Non-smoker
排除标准
- •Aged >80 years
- •Inability to comply with study procedures
- •Currently participating or having participated in another infusion trial during last 12 months
- •Any acute or chronic llness
- •History of neuromuscular problems
- •Medications known to affect protein metabolism
- •Individuals who complete fewer than 5000 steps per day
- •Individuals who have metal implants
结局指标
主要结局
Change in myofibrillar fractional synthetic rate (FSR)
时间窗: one day and 2 weeks
次要结局
- change in non-myofibrillar fractional synthetic rate (FSR)(baseline and one day of feeding)
- Capillary dilatation and blood flow(2 weeks)
研究者
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