Effects of an intravenous acetaminophen/ibuprofen fixed-dose combination on catheter- related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study
- Conditions
- Diseases of the genitourinary system
- Registration Number
- KCT0007640
- Lead Sponsor
- Konyang University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Male
- Target Recruitment
- 106
1. Male patients aged 19 to 70 who require catheterization in the operating room during urology surgery
2. According to the American Society of Anesthesiologist's physical status classification, 1 to 3 patients.
-Benign prostatic hyperplasia
- Patients with overactive bladder symptoms (frequent urination 3 or more times at night or 8 or more times in 24 hours)
- Patients with bladder outlet and lower urinary tract obstruction
- Psychiatric patients
- Patients with cognitive impairment
- Contraindicated use of acetaminophen or ibuprofen (e.g., history of hypersensitivity reactions, gastrointestinal ulcers, severe renal impairment)
- Patients with active alcoholism
- Patients with severe blood abnormalities, liver disorders, kidney disorders, heart failure, and high blood pressure
- Patients with bronchial asthma or a history
- Patients with pain before and after coronary artery bypass surgery
- If patients are taking concomitant medications (eg, barbiturates, tricyclic antidepressants, high-dose methotrexate)
- In other cases where the researcher is considered inappropriate
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method catheter related bladder discomfort
- Secondary Outcome Measures
Name Time Method Time to extubation, sedation level, pain level, emergence agitation, requirement of analgesic, requirement of antiemetic, and other discomfort complained by the patient after surgery, catheter related bladder discomfort in the ward