Effects of an intravenous acetaminophen/ibuprofen fixed-dose combination on postoperative sore throat in patients undergoing gynecological surgery: a prospective, randomized, placebo-controlled, double-blind study
- Conditions
- Diseases of the genitourinary system
- Registration Number
- KCT0007641
- Lead Sponsor
- Konyang University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Female
- Target Recruitment
- 108
1. Female patients aged 19 to 64 who require endotracheal intubation during gynecological surgery
2. According to the American Society of Anesthesiologist's physical status classification, 1 to 3 patients.
- Patients with sore throat, cough, and hoarseness before surgery
- Patients with symptoms of upper respiratory tract infection before surgery
- Patients who are expected difficult intubation
- Psychiatric patients
- Patients with cognitive impairment
- Contraindicated use of acetaminophen or ibuprofen (e.g., history of hypersensitivity reactions, gastrointestinal ulcers, severe renal impairment)
- When the surgical method is changed from laparoscopic to laparotomy during surgery
- Patients with active alcoholism
- Patients with severe blood abnormalities, severe liver disorders, severe kidney disorders, severe heart failure, and severe hypertension
- Patients with asthma or a history
- Patients with pain before and after coronary artery bypass surgery
- If you are taking concomitant medications (eg, barbiturates, tricyclic antidepressants, high-dose methotrexate)
- In other cases where the researcher is considered inappropriate
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method postoperative sore throat
- Secondary Outcome Measures
Name Time Method time to extubation, emergence agitation, pain grade, requirement of analgesic, postoperative sore throat at the ward.