Comparison of the Long-Term Success of Different CAD-CAM Blocks Used as Indirect Restorations in Molar Incisor Hypomineralized Teeth: A Split Mouth Study

Not Applicable

Completed

• Conditions: Molar Hypomineralization, Incisor

• Registration Number: NCT07144605
• Lead Sponsor: Necmettin Erbakan University

Brief Summary

This study is about the long-term survival success of different, externally prepared fillings (Indirect restoration, CAD-CAM blocks) used in teeth with reduced mineral structure, namely Molar Incisor Hypomineralization (MIH), which is called chalk teeth in children.

Detailed Description

The aim of this study was to comparatively evaluate the long-term survival times and clinical success of nano-ceramic hybrid CAD-CAM blocks, Grandio Blocs (R) (VOCO), and glass-ceramic blocks, GC INITIAL LiSi (GC AMERICA INC. USA), according to USPHS criteria, after pulpal treatment in mandibular teeth with bilateral moderate molar incisor hypomineralization.

Study Timeline

• Study Start: 2024-06-15
• Primary Completion: 2024-07-20
• Study First Submitted: 2025-07-15
• Study Completion: 2025-07-20
• Status Verified: 2025-08
• Study First Submitted QC: 2025-08-20
• Last Update Submitted: 2025-08-20
• Study First Posted: 2025-08-27
• Last Update Posted: 2025-08-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

8-15 years old

• Systemically healthy
• Cooperative (Frankl 3-4)
• Diagnosed with MIH for at least one permanent tooth
• Symmetrical mandibular molars that fit the middle MIH classification (teeth with a tooth score of 7-9 in MIHSI)
• Teeth without indication for root canal treatment
• Teeth without percussion, abscess and fistula formation
• Without periapical lesions
• With post-eruption enamel fractures in the relevant teeth
• Without mobility and pathological gingival pockets
• Patients who agreed to participate in the study.

Exclusion Criteria

Teeth that are suitable for mild and severe classification

• Non-cooperative (Frankl 1 and Frankl 2)
• Teeth with extraction indication
• Teeth that require root canal treatment
• Teeth with periapical lesions, abscesses and fistula formation
• Patients with mobility and pathological gingival pockets

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the clinical status of the restorations	up to 6 months after intervention	The restorations were clinically evaluated in the oral cavity using the USPHS index.
the status of the periapical tissues	Up to the 6th months	The periapical tissue status was assessed according to the Periapical Index (PAI).

Trial Locations

Locations (1)

Necmettin Erbakan University; Konya, Meram, Turkey (Türkiye)