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Clinical Trials/NCT06649916
NCT06649916
Recruiting
N/A

Autism Word Learning and Infant Directed-Speech

The University of Texas at Dallas1 site in 1 country100 target enrollmentOctober 4, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism
Sponsor
The University of Texas at Dallas
Enrollment
100
Locations
1
Primary Endpoint
Proportion of time during which children's eye gaze is directed toward the target object
Status
Recruiting
Last Updated
6 months ago

Overview

Brief Summary

The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

Detailed Description

Caregivers frequently use parentese, also known as infant-directed speech (IDS), when speaking to young children. Compared to adult registered speech, parentese is typically characterized by greater pitch variation, longer duration, and louder volume. Parentese facilitates early language development in typically developing (TD) children. However, it remains unknown whether the facilitative effect of parentese on language learning can be generalized to clinical populations such as autistic children given that core autism features (e.g., sensory and social communication differences) may interact with how they process and learn from parentese. Most autistic children do not reach age-appropriate language ability even if they receive timely early intervention. Determining if autistic children can learn language from parentese, a common way language input is provided to young children, is a critical first step toward understanding whether language input needs to be adjusted to optimize their language development. The overall objective of this research is to determine whether parentese facilitates novel word learning in autistic children and to investigate if the effect of parentese is conditional upon input factors (recorded parentese vs live parentese presented in social interaction) and child factors (extreme responses to auditory input, social motivation). In Aim 1, the investigators will use a video-based word learning paradigm to determine the effect of recorded parentese on novel word learning in autistic children compared to language-matched TD peers. Aim 2 focuses on the effect of live parentese on novel word learning: an experimenter will teach children two novel words, presented in live parentese or live parentese, during social interaction. Aim 3 will examine whether child factors (extreme responses to auditory input, social motivation) explain variability in word learning accuracy from recorded parentese and live parentese in the autistic group. Children's extreme responses to auditory input (including hyper- and hypo-responsiveness) and social motivation will be measured using caregiver questionnaires and will be used to predict word learning accuracy from recorded parentese (Aim 1) and live parentese (Aim 2) in the autistic group.

Registry
clinicaltrials.gov
Start Date
October 4, 2024
End Date
March 1, 2028
Last Updated
6 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Pumpki Lei Su

Assistant Professor

The University of Texas at Dallas

Eligibility Criteria

Inclusion Criteria

  • children with or without a diagnosis of ASD between 18 and 59 months

Exclusion Criteria

  • hears another language more than 10% of time based on parent report
  • has uncorrected visual impairment or hearing impairment
  • has developmental disorders or medical conditions other than ASD that affect language or cognition (excepting psychiatric conditions often comorbid with ASD such as ADHD)

Outcomes

Primary Outcomes

Proportion of time during which children's eye gaze is directed toward the target object

Time Frame: 300 ms after the target words are introduced

Children's eye gaze is recorded as they look at images. The proportion of time during which gaze is directed to an image of the targeted word is the dependent measure.

Study Sites (1)

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