Randomized Control Trial of Weaning NCPAP From Preterm Infants: Sudden Wean Versus Weaning by Gradually Decreasing Pressure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Success of weaning on first trial off NCPAP
研究概览
简要总结
To compare the 2 methods of weaning of nasal continuous positive airway pressure (CPAP) in premature babies born between 26 and 32 weeks
详细描述
To study the weight and the post menstrual age (PMA) at the time of NCPAP wean utilizing the method of sudden wean as compared to gradual wean.
Methods: A prospective randomized trial was conducted comparing sudden weaning with gradual weaning from NCPAP in neonates with gestational age between 26 and 32 weeks. The patients were randomized to one of the two methods of weaning from NCPAP and their success was compared
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 26 Weeks 至 32 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All neonates born 26 to 32 weeks of gestational age
排除标准
- •Those with severe congenital anomalies and chromosomal defects including congenital heart disease, neurological malformations, chest and airway abnormalities and lung hypoplasia
研究组 & 干预措施
Sudden wean
When ready Nasal Continuous Positive Airway Pressure (NCPAP) will be removed from the neonate
Gradual pressure wean
NCPAP will be removed by gradually decreasing pressure over 24 hours once the weaning is decided
干预措施: Gradual pressure wean (Other)
结局指标
主要结局
Success of weaning on first trial off NCPAP
时间窗: Completion of Nasal Continuous Positive Airway Pressure (NCPAP) treatment, expected average of 4 weeks
次要结局
- Weight and corrected GA when come off oxygen(when off supplemental oxygen expected average of 2 weeks)
- Weight and corrected gestational age (GA) when neonates could come off NCPAP(Completion of Nasal Continuous Positive Airway Pressure (NCPAP) treatment, expected average of 4 weeks)