Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease; Asthma
• Interventions: Dietary Supplement: Mablet (Magnesium-supplement); Drug: Magnesium Sulfate

• Registration Number: NCT01113138
• Lead Sponsor: University of Aarhus

Brief Summary

The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that daily magnesium supplement will benefit patients with asthma and chronic obstructive pulmonary disease.

The aim of this part of the project is to study the pharmacokinetics of the following two magnesium supplements:

* Mablet (dietary supplement)

* Magnesium Sulfate (solution for infusion)

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-04-27
• Study First Submitted QC: 2010-04-28
• Study First Posted: 2010-04-29
• Study Start: 2012-12
• Status Verified: 2014-01
• Primary Completion: 2014-01
• Study Completion: 2014-01
• Last Update Submitted: 2014-01-10
• Last Update Posted: 2014-01-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• Healthy volunteers.

Exclusion Criteria

• Smokers,
• Using pharmaceuticals/supplements,
• Vegans/vegetarians,
• Major changes in eating habits within one week prior to study start.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Mablet	Mablet (Magnesium-supplement)	-
Magnesium sulfate	Magnesium Sulfate	-

Primary Outcome Measures

Name	Time	Method
Pharmacokinetic parameters	Two years	Clearance, half-life \& absorption fraction

Trial Locations

Locations (1)

Research Dept. of Respiratory Medicine, Aarhus University Hospital; 🇩🇰 Aarhus C, Denmark