COMPARISON OF EFFICACY OF ORAL AMOXICILLIN VERSUS PARENTERAL CEPHALOSPORIN IN TREATMENT OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA A PROSPECTIVE SINGLE BLINDED PARALLEL DESIGN,RANDOMIZED CONTROL TRIAL IN A TERTIARY CARE HOSPITAL OF METROPOLITAN CITY.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- COMPARISON OF EFFICACY OF ORAL AMOXICILIN VERSUS PARENTERAL CEPHALOSPORIN IN CASE OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN IN TERMS OF DAY OF DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTIC, DURATION OF HOSPITAL STAY
研究概览
简要总结
THIS STUDY IS PROSPECTIVE, SINGLE BLINDED, PARALLEL DESIGN, RANDOMIZED CONTROL TRIAL COMPARING THE EFFICACY OF ORAL AMOXICILLIN VERSUS PARENTERAL CEPHALOSPORIN IN TREATMENT OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA CONDUCTED IN TERTIARY CARE HOSPITAL GRANT GMC AND JJ HOSPTAL, MUMBAI IN PAEDIATRIC WARD OVER THE DURATION OF 18 MONTHS. PRIMARY OUTCOME MEASURES IN TERMS OF DAY DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTICS AND DURATION OF HOSPITAL STAY.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 6.00 Month(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •ALL CHILD IN THE AGE GROUP OF 6 MONTHS TO 12 YEARS ADMITTED IN PAEDIATRIC WARD AND CLINICALLY DIAGNOSED AS UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IRRESPECTIVE OF ETIOLOGY.
排除标准
- •LESS THAN 6 MONTHS OF AGE.
- •CHILD ADMITTED IN PAEDIATRIC INTENSIVE CARE UNIT.
- •CHILD WITH UNDERLYING IMMUNODEFICIENCY INCLUDING ACQUIRED AND CONGENITAL CAUSES.
- •CHILD WITH CO-MORBID CONDITIONS LIKE DENGUE, MEASLES ETC.
- •CHILD WITH UNDERLYING HEREDITARY DISORDER LIKE CYSTIC FIBROSIS, SICKLE CELL DISEASE, DISORDERS OF CILIA ETC.
- •CHILD WITH UNDERLYING ANATOMICAL DISORDER LIKE PULMONARY SEQUESTRATION, LOBAR PNEUMONIA, GASTROESOPHAGEAL REFLUX DISORDER, TRACHEOESOPHAGEAL FISTULA AND BRONCHOPULMONARY DYSPLASIA.
结局指标
主要结局
COMPARISON OF EFFICACY OF ORAL AMOXICILIN VERSUS PARENTERAL CEPHALOSPORIN IN CASE OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN IN TERMS OF DAY OF DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTIC, DURATION OF HOSPITAL STAY
时间窗: 18 MONTHS
次要结局
- COMPARISON OF EFFICACY OF ORAL AMOXICILIN VERSUS PARENTERAL CEPHALOSPORIN IN CASE OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN IN TERMS OF DAY OF DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTIC, DURATION OF HOSPITAL STAY(18 MONTHS)