Proportional Assist Ventilation with adjustable gain factors versus Pressure Support ventilation in critically ill patients
Completed
- Conditions
- Respiratory disorders requiring mechanical ventilationRespiratoryRespiratory disorders
- Registration Number
- ISRCTN00104615
- Lead Sponsor
- Cretan Critical Care Society (Greece)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
1. Critically ill patients receiving control mechanical ventilation for at least 36 hours
2. Partial Pressure of Oxygen in Arterial Blood (PaO2) more than 65 mmHg, Fraction of Inspired Oxygen (FiO2) less than 65% and Positive End Expiratory Pressure (PEEP) level less than 15 mmHg
3. No respiratory distress
Exclusion Criteria
1. Aged over 18 and under 85 years
2. Severe haemodynamic instability
3. Pregnancy
4. Neuromuscular disorders
5. End stage disease
6. Severe bronchospasm, resistance of the respiratory system more than 20
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. PAV success rate<br>2. Sedation doses
- Secondary Outcome Measures
Name Time Method 1. Weaning time<br>2. Intensive Care Unit (ICU) mortality<br>3. Hospital mortality