Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression
- Conditions
- Major Depressive Disorder
- Interventions
- Behavioral: Group IPT for Depression + TAU
- Registration Number
- NCT01685294
- Lead Sponsor
- Brown University
- Brief Summary
This study will examine the effects of a first-line treatment for major depressive disorder (MDD), interpersonal psychotherapy (IPT), among men and women prisoners.
- Detailed Description
The purpose of this 3-year randomized trial is to promote uptake of evidence-based treatment in criminal justice settings by conducting a fully-powered randomized effectiveness study that collects pilot implementation data, including cost-effectiveness data. Group IPT will be compared to treatment as usual (TAU) in a sample of 90 male and 90 female prisoners with MDD from 4 institutions, allowing us to explore gender effects.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 181
- Meet all DSM-IV criteria for primary (non-substance induced) major depressive disorder
- Expectation of at least 6 months of incarceration at baseline interview
- Incarcerated for at least 4 weeks
-
Lifetime:
- Bipolar disorder
- Psychotic disorder
-
Are imminently suicidal
-
Cannot understand English well enough to understand the consent form or assessment instruments when read aloud
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group Interpersonal Psychotherapy (IPT) for Depression + TAU Group IPT for Depression + TAU Participants will receive Group IPT for Depression + TAU.
- Primary Outcome Measures
Name Time Method Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 3 Months 3 Months from Baseline
- Secondary Outcome Measures
Name Time Method Change from Baseline in Suicidality at 6 Months 6 Months from Baseline Suicidality as measured by the Beck Scale for Suicide Ideation.
Cost-effectiveness 6 months post-baseline Cost-effectiveness based on costs of IPT and TAU, improvements in HRSD scores, LIFE scores, and cost-offsets, including medical costs, programs completed, fewer fights, fewer suicide attempts, and reduced length of incarceration due to more "good time."
Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 6 Months 6 Months from Baseline Change from Baseline in Suicidality at 3 Months 3 Months from Baseline Suicidality as measured by the Beck Scale for Suicide Ideation.
Change from Baseline in In-Prison Functioning at 3 Months 3 Months from Baseline In-prison functioning will be assessed by the number of correctional programs enrolled/completed and disciplinary/incident reports (measured by the Timeline Followback); aggression/victimization (measured by the Conflict Tactics Scale 2); social support (measured by the Multidimensional Scale of Perceived Social Support and the UCLA Loneliness Scale)
Change from Baseline in In-Prison Functioning at 6 Months 6 Months from Baseline In-prison functioning will be assessed by the number of correctional programs enrolled/completed and disciplinary/incident reports (measured by the Timeline Followback); aggression/victimization (measured by the Conflict Tactics Scale 2); social support (measured by the Multidimensional Scale of Perceived Social Support and the UCLA Loneliness Scale)
Trial Locations
- Locations (5)
Massachusetts Correctional Institute - Old Colony Correctional Center
🇺🇸Bridgewater, Massachusetts, United States
Massachusetts Correctional Institution - Framingham
🇺🇸Framingham, Massachusetts, United States
Massachusetts Correctional Institution - Norfolk
🇺🇸Norfolk, Massachusetts, United States
South Middlesex Correctional Center
🇺🇸Framingham, Massachusetts, United States
Adult Correctional Institution - Men's & Women's Medium & Minimum Security Facilities
🇺🇸Cranston, Rhode Island, United States