NL-OMON45184
Completed
Not Applicable
In Vivo Imaging of Neuroinflammation in Simvastatin-Treated Schizophrenic Patients - Neuroinflammation in SIM-treated SCZ patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 75
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Control subjects
- •\> Age between 18 and 50 years.;Schizophrenic patients
- •Fulfilling the inclusion of the core study, which are:
- •\> Age between 18 and 50 years;
- •\> A DSM\-IV\-R diagnosis of: 295\.x (schizophrenia, schizophreniform disorder, or schizoaffective disorder) or 298\.9 (psychosis NOS);
- •\> Onset of first psychosis no longer than 3 years ago;
- •\> Female patients of childbearing potential need to utilize a proper method of contraception (the pill, vaginal ring, hormonal patch, intrauterine device, cervical cape, condom, contraceptive injection, diaphragm) in case of sexual intercourse during the study.
Exclusion Criteria
- •Control subjects
- •\> Women who are pregnant;
- •\> Women who intend to get pregnant during the study;
- •\> Use or having used psychotropic medication in the past six months;
- •\> Alcohol or substance abuse in the past 3 months;
- •\> Taking any medication, except oral contraceptives;
- •\> Evident somatic/psychiatric co\-morbidity;
- •\> First\-degree relatives with (a history of) schizophrenia or schizophrenia spectrum disorders;
- •\> Participation in a scientific research study during the past year involving radiation;
- •\> Presence of materials in the body that can be magnetized and cannot be removed.;Schizophrenic patients
Outcomes
Primary Outcomes
Not specified
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