Classification of Adult-onset Diabetes in Five Subgroups in Pakistani Population
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 394
- 主要终点
- Classify patients into data-driven clusters (e.g., severe insulin-deficient, severe insulin-resistant, mild obesity-related and mild age-related diabetes).
研究概览
简要总结
This study aims to classify adult-onset diabetes patients into distinct data-driven clusters, such as severe insulin-deficient, severe insulin-resistant, mild obesity-related, and mild age-related diabetes, based on clinical and biochemical characteristics. Using a cross-sectional design, data will be collected from individuals attending outpatient diabetes clinics at tertiary care hospitals in Pakistan. The study will analyze the distribution of metabolic and demographic characteristics within each cluster and assess subgroup-specific risks for diabetic complications. Additionally, the relationship between clustering variables and the risk of complications will be evaluated to enhance the understanding of diabetes heterogeneity and its impact on patient outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of both genders whose age of disease onset was older than 16 years
- •Patients newly diagnosed with or previously diagnosed with T2D
- •Able and willing to provide written informed consent and to comply with the study
排除标准
- •Patients with other medical comorbidities (not a complication of diabetes), such as malignancies.
- •Pregnancy
结局指标
主要结局
Classify patients into data-driven clusters (e.g., severe insulin-deficient, severe insulin-resistant, mild obesity-related and mild age-related diabetes).
时间窗: At the time of clinic visit during enrollment
次要结局
- Analyze the distribution of metabolic and demographic characteristics within each cluster.(At the time of clinic visit during enrollment)
- • Assess subgroup-specific risks for diabetic macrovascular complications such as CVD, Stroke/TIA, and microvascular complications such as nephropathy, retinopathy, peripheral and autonomic neuropathy(At the time of clinic visit during enrollment)
- Evaluate the relationship between clustering variables and complications.(At the time of clinic visit during enrollment)