NCT02691403Unknown4 期
Ultrasound-guided Quadratus Lumborum Block for Postoperative Analgesia After Colostomy: A Randomized Controlled Trial
Sun Yat-sen University0 个研究点目标入组 50 人开始时间: 2016年3月最近更新:
适应症
干预措施
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 50
- 主要终点
- cumulative morphine consumption
研究概览
简要总结
Patients undergoing abdominal procedures often require multimodal postoperative pain controls. Truncal blocks such as quadratus lumborum (QL) block may be used adjunctively as a part of it. The investigators hypothesized that the ultrasound-guided QL block with transmuscular approach can provide adequate pain relief for colostomy closure as part of a multimodal pain control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A physical status between ASA I and III
- •20 - 75 years of age
- •Patient has signed an informed consent
- •Without contraindication of QL block
- •Exclusion Criteria
- •American Society of Anesthesiologists (ASA) Physical Status ≥ 4
- •Any contraindication to nerve blocks (including coagulopathy, abnormal anatomy, infection at the planned QL injection site, and amide-type local anesthetic allergy) pregnancy or breast-feeding
- •Severe obesity (body mass index≥ 35 kg/m2)
- •Patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease
- •Allergy to NSAIDs
- •Infection at the QL injection site
- •Patients with major psychosis or drug and alcohol abuse
- •Patient unable to comprehend or use the verbal rating pain scoring system or patient-controlled analgesia pump
排除标准
- 未提供
研究组 & 干预措施
Placebo QL block
Sham Comparator
30 ml single shot QL block with saline 0.9%
干预措施: normal saline (Drug)
Active QL block
Active Comparator
30 ml single shot QL block with 0.25% levo-bupivacaine
干预措施: levo-bupivacaine (Drug)
结局指标
主要结局
cumulative morphine consumption
时间窗: 1 hour
次要结局
未报告次要终点
研究者
Nai Liang Li
Doctor
Sun Yat-sen University
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Unknown
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