Impact of CKD on Children and Their Families
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D
- Interventions
- Other: functional capacityOther: muscle strengthOther: Quality of life of childrenOther: Quality of life of families
- Registration Number
- NCT04538443
- Lead Sponsor
- Cairo University
- Brief Summary
Based on the available literatures, previous studies have investigated the impact of CKD and dialysis on patient's health among adult and elderly population. As far as we know, this is the first empirical study that investigates the impact of CKD on children functional capacity and their families QOL.
- Detailed Description
The current study will be done to investigate the long term effect of the CKD itself on different dimensions of the child health to understand the unique characteristics of pediatric CKD. Also, it will be beneficial for designing a comprehensive physical therapy protocol for prevention of different complications and to improve their wellbeing healthcare. Additionally, it will be beneficial to determine the family and parental stresses and to build the rehabilitation plan for the child considering the possible family issues regarding the child condition.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- Age from eight to twelve years.
- Both genders.
- Diagnosed with ESRD (stage 5) based on the glomerular filtration rate (GFR < 15 mL/minute/1.73 m2).
- Able to understand and follow instructions during assessment procedures.
- Willing to participate in the study and attend the assessment procedures.
Children of the following criteria will be excluded from the study:
- Cardiopulmonary disorders
- Uncontrolled hypertension
- Unstable angina
- Severe uncontrolled diabetes
- Neurological or cognitive disorders with functional deficits
- Significant cerebral or peripheral vascular disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description hemodialysis group functional capacity One hundred children with ESRD who are treated with hemodialysis and their caregivers will participate in this study. They will be recruited from Nephrology Unit at Abo-Elreesh Hospital, Cairo University hemodialysis group Quality of life of families One hundred children with ESRD who are treated with hemodialysis and their caregivers will participate in this study. They will be recruited from Nephrology Unit at Abo-Elreesh Hospital, Cairo University hemodialysis group muscle strength One hundred children with ESRD who are treated with hemodialysis and their caregivers will participate in this study. They will be recruited from Nephrology Unit at Abo-Elreesh Hospital, Cairo University hemodialysis group Quality of life of children One hundred children with ESRD who are treated with hemodialysis and their caregivers will participate in this study. They will be recruited from Nephrology Unit at Abo-Elreesh Hospital, Cairo University
- Primary Outcome Measures
Name Time Method functional capacity 6 months 6 minute walking test is commonly used to evaluate functional capacity in children with CKD. It is a simple, practical, reliable, and valid measure of submaximal exercise capacity in healthy children and children with chronic disease or neuromuscular disorders or cardiopulmonary disease
- Secondary Outcome Measures
Name Time Method quality of life of families of children with CKD 6 months The PedsQL FIM appears to be a useful tool for the assessment of family impact on children with ESRD
muscle strength 6 months Hand grip strength HGS is a noninvasive and reliable method for assessment of muscle power and nutritional status in CKD children
quality of life of children 6 months The Arabic version of the PedsQLTM 4.0 Generic Core Scales version proved to be understandable and feasible to use. It showed good reliability for healthy children and children with chronic medical conditions and their parents.