EFFECTS OF BETA 2 RECEPTOR BLOCKADE ON PULMONARY FUNCTION IN A HUMAN MODEL OF ACUTE HYDRIC OVERLOAD

• Conditions: BETA BLOCKADE AND LUNG FUNCTION; Therapeutic area: Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09]

• Registration Number: EUCTR2010-020357-14-IT
• Lead Sponsor: FONDAZIONE MONZINO CENTRO CARDIOLOGICO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03-06
• Last Update Posted: 25 September 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

healthy subjects aging between 30 and 60 yearsl
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 20
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

pregnancy, or breast feeding, CoPD

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: to avaluate the effects of beta 2 receptor blockade on pulmonary function in healthy subjects after water load;Secondary Objective: none;Primary end point(s): absolute or percentage variations of DLCO;Timepoint(s) of evaluation of this end point: before and after 7 days of treatment

Secondary Outcome Measures

Name	Time	Method
Secondary end point(s): none;Timepoint(s) of evaluation of this end point: -