Comparison of efficacy and safety of chlorthalidone against hydrochlorthiazide in combiantion with telmisartan in patients with hypertensio
Phase 4
- Conditions
- Health Condition 1: I10- Essential (primary) hypertension
- Registration Number
- CTRI/2022/10/046669
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient diagnosed with hypertension and SBP between 140 and 159 Mm Hg and DBP between 90 and 99 Mm Hg.
Exclusion Criteria
1.Hypertensive emergency/urgency
2.Known case of other cardiovascular disease.
3.Known case of diabetes mellitus
4.Pregnant women
5.Patient unwilling to participate in trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in 24 hours mean systolic and diastolic ambulatory blood pressure (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month
- Secondary Outcome Measures
Name Time Method 1.Comparison of change in mean systolic and diastolic office blood pressure (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;2.Comparison of change in night time systolic and diastolic blood pressure (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;3.Comparison of serum potassium, sodium, uric acid level (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;4.Comparison of renal and liver function (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;5.Comparison of lipid profile (follow up at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;6.HbA1c (baseline and at the end of 3rd month)Timepoint: Baseline and at the end of 3rd month;7.Comparison of any other adverse effect reported by the patientsTimepoint: Baseline and at the end of 3rd month;8.Comparison of rescue medication used to control blood pressureTimepoint: Baseline and at the end of 3rd month