Effect of Hemodialysis Membranes on Platelet Count

Completed

• Conditions: Thrombocytopenia

• Registration Number: NCT01356576
• Lead Sponsor: Northwell Health

Brief Summary

The purpose of this study is to determine if there is a drop in platelet count after hemodialysis. Hemodialysis membranes are known to activate complement and cause a drop in platelets and sometimes in white blood cells. The investigators are going to study one of the membranes which is the Fresenius Optiflux® to check if it causes a drop in platelets.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2011-05-13
• Study First Submitted QC: 2011-05-18
• Study First Posted: 2011-05-19
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-06
• Last Update Posted: 2014-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

• Patients on Hemodialysis for >=6 months

Exclusion Criteria

• Hematological Cancers

  • Myelodysplastic syndromes
  • Baseline thrombocytopenia
  • Acute infections (patients on antibiotics)
  • Patients with Immune thrombocytopenic purpura (ITP)/Thrombotic thrombocytopenic purpura (TTP)
  • HIV
  • Liver disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Drop in platelet counts	90 minutes through hemodialysis and immediately after finishing hemodialysis

Trial Locations

Locations (1)

Island Rehabilitative Service; 🇺🇸 Staten Island, New York, United States