Investigating Distress Tolerance in Adults With Tourette Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Distress Tolerance Scale (DTS)
研究概览
简要总结
Although behavior therapy is recognized as a first-line intervention for Tourette's Disorder (TD), less than 40% of adults with TD respond to this evidence-based treatment. Limited tolerance for aversive premonitory urges and affective states that accompany tics may be one likely factor that impedes behavior therapy outcomes. This study examines the relationship between distress tolerance and tic inhibition among adults with TD, and investigates the mechanism and effect of therapeutic skills training to enhance distress tolerance abilities. Findings will determine the optimal approach to enhance distress tolerance among adults with TD and ultimately lead to better behavior therapy outcomes.
详细描述
Tourette's Disorder and other persistent tic disorders collectively affect about about 1% of the population, cause significant distress, and functional impairment. Although behavior therapy is recognized as a first-line intervention for Tourette's Disorder (TD), less than 40% of adults with TD respond to this evidence-based treatment. Limited tolerance for aversive premonitory urges and affective states that accompany tics may be one likely factor that impedes behavior therapy outcomes. This study examines the relationship between distress tolerance and tic inhibition among adults with TD, and investigates the mechanism and effect of therapeutic skills training to enhance distress tolerance abilities.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants will be eligible for participation if the following inclusion criteria are met:
- •at least 18 years of age
- •have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater than 14 (>9 for adults with motor or vocal tics only)
- •exhibit a tic frequency of at least one visible tic per minute
- •be fluent in English
- •have a total premonitory urge for tics scale (PUTS) total score greater than 17 at Visit 2
- •have a total DTS score greater than 30 at Visit 2
排除标准
- •for participants include:
- •history of cardiovascular disorder
- •history of fainting or seizures
- •history of frostbite
- •open cut or sore on hand to be immersed
- •fracture to the limb to be immersed
- •history of Reynaud's phenomenon
- •inability to complete rating scales
- •inability to attend study visits
研究组 & 干预措施
Distress Tolerance Skills Training
Distress tolerance skills training is a multicomponent intervention drawn from third-wave cognitive-behavioral therapy (CBT) protocols.
干预措施: Distress Tolerance Skills Training (Behavioral)
结局指标
主要结局
Distress Tolerance Scale (DTS)
时间窗: Within 1 week after completion of Distress Tolerance Skills Training
The Distress Tolerance Scale is a 15-item self-report measure that measures the perceived capacity to tolerate distress from a multidimensional framework, including tolerance, appraisal, absorption, and regulation. Items are rated on a 1-5 Likert scale, and then summed. Score ranges from 15-75. Higher total scores indicate greater difficulty with tolerating distress.
次要结局
- Yale Global Tic Severity Scale-Revised (YGTSS)(Within 1 week after completion of Distress Tolerance Skills Training)