Normal Paranasal Sinuses Microflora Study

Completed

• Conditions: Paranasal Sinuses; Flora

• Registration Number: NCT00426569
• Lead Sponsor: Sheba Medical Center

Brief Summary

The purpose of this study is to check if bacterial and fungal flora exists in healthy paranasal sinuses, and whether it is identical to the flora of nasal cavity.

We plan to harvest tiny examples of maxillary sinus and nasal mucosa for tissue cultures during the orthognathic procedures involving maxillary remodeling.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-01-23
• Study First Submitted QC: 2007-01-23
• Study First Posted: 2007-01-24
• Study Start: 2007-02
• Primary Completion: 2015-04
• Status Verified: 2015-05
• Study Completion: 2015-05
• Last Update Submitted: 2015-05-22
• Last Update Posted: 2015-05-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Necessity of maxillary sinus opening during orthognathic surgery
• Negative history of chronic rhinitis or chronic sinusitis
• Informed concent

Exclusion Criteria

• Recent(1 month or less before the operation) event of acute sinusitis or other disease leading to nasal discharge
• Recent(1 month or less before the operation) antibacterial or antifungal parenteral treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
presence of bacteria in normal paranasal sinuses	at time of orthgnatic surgery

Trial Locations

Locations (1)

Sheba Medical Center; 🇮🇱 Tel Hashomer, Israel