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Clinical Trials/ISRCTN14732774
ISRCTN14732774
Completed
Not Applicable

Adoptive immunotherapy for adenovirus (AdV)-associated complications post transplantatio

Charité - University Medicine Berlin (Germany)0 sites306 target enrollmentStarted: March 31, 2006Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Charité - University Medicine Berlin (Germany)
Enrollment
306

Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Sex
All

Inclusion Criteria

  • Pediatric patients, aged 2 to 18 years with:
  • 1\. Acute leukemias (ALL)
  • 2\. Acute myeloid leukemia (AML)
  • 3\. Chronic myeloid leukemia (CML)
  • 4\. Myelodysplastic syndromes (MDS)

Exclusion Criteria

  • 1\. Patients in relapse or progress of AML or ALL and blast crisis of CML at the time of randomization
  • 2\. All second transplants
  • 3\. AdV seronegative recipients with seronegative matched related donors (MRD)
  • 4\. Patients with severe non\-hematopoietic organ toxicity grade 3\-5 (according to the National Cancer Institute \[NCI] and Cancer Therapy Evaluation Program \[CTEP] reporting criteria) at the time of randomization

Investigators

Sponsor
Charité - University Medicine Berlin (Germany)

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