Continuous EEG registration and surveillance at the NICU in neonates with hypoxic-ischemic encephalopathy

Completed

• Conditions: lack of oxygen during birth; perinatal asphyxia; 10039911

• Registration Number: NL-OMON29983
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

neonates with gestational duration * 35 weeks with an arterial umbilical pH < 7,00 or an Apgar score * 5 at 5 minutes, present within 24 h after birth at the neonatal intensive care unit of the VU medical center.

Exclusion Criteria

Premature neonates; Suspected chromosomal/syndromal abnormalities or metabolic disturbances. Neonates with a skull defect. Inability from the Clinical Neurophysiological (CNP) unit to register the EEG.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Analysis:<br /><br>Sensitivity and false positive rates will be calculated for each detection<br /><br>method. The visual inspected EEG will be used as gold standard and will be<br /><br>compared with the 9 and 21 channel EEG with SL detection and the practical<br /><br>standard, the aEEG. Furthermore, the correlation between the detection method<br /><br>will be assessed with the Spearman Ranks. A p value <0.05 will be designated as<br /><br>statistically significant. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na</p><br>